Transport processes in urinary acidification
نویسندگان
چکیده
منابع مشابه
Urinary acidification: CO2 transport by the rabbit proximal straight tubule.
Proximal straight tubules from rabbit kidneys were perfused in vitro in order to study transport of bicarbonate. Total CO2 content was measured in perfused and collected tubule fluid, using microcalorimetry. When the initial perfusate and bath contained 25 mM bicarbonate, the concentration of total CO2 decreased in the collected tubule fluid, indicating net reabsorption of bicarbonate. When the...
متن کاملProton ATPases and urinary acidification.
Acidification of the urine is mediated by vectorial H+ transport from cells at a number of sites in the kidney. A proton ATPase has been described that appears to mediate a significant proportion of this H+ transport. In particular, in proximal tubule and collecting duct, there is evidence both for the presence of transporter protein and for H+ transport with features that have been identified ...
متن کاملA mathematical model of rat collecting duct. I. Flow effects on transport and urinary acidification.
A mathematical model of the rat collecting duct (CD) has been developed by concatenating previously published models of cortical (Weinstein AM. Am J Physiol Renal Physiol 280: F1072-F1092, 2001); outer medullary (Weinstein AM. Am J Physiol Renal Physiol 279: F24-F45, 2000); and inner medullary segments (Weinstein AM. Am J Physiol Renal Physiol 274: F841-F855, 1998). Starting with end-distal tub...
متن کاملDefect in urinary acidification induced in vitro by amphotericin B.
An experimental defect in urinary acidification was induced in the isolated turtle bladder by amphotericin B and the nature of the defect was examined. Net hydrogen ion secretion was little affected by amphotericin when passive electrochemical forces across the epithelium were held at a minimum in the short-circuited state under isohydric conditions. Hydrogen ion secretion against a gradient, h...
متن کاملStudy of urinary acidification in patients with idiopathic hypocitraturia.
Hypocitraturia (HCit) is one of the most remarkable features of renal tubular acidosis, but an acidification defect is not seen in the majority of hypocitraturic patients, whose disease is denoted idiopathic hypocitraturia. In order to assess the integrity of urinary acidification mechanisms in hypocitraturic idiopathic calcium stone formers, we studied two groups of patients, hypocitraturic (H...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 1976
ISSN: 0085-2538
DOI: 10.1038/ki.1976.19